Addiction
Addiction |
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| Condition | Substance | Evidence Level | Type of Evidence |
|---|---|---|---|
| Addiction (alcohol, cocaine, heroin) | Ketamine Clinical Use Legal in the US |
B | Randomized Controlled Trials (1 or more) |
| Addiction (alcohol) | Psilocybin Not legal in the US; FDA-Approved Clinical Research |
B | Randomized Controlled Trials (1 or more) |
| Addiction (tobacco) | Psilocybin Not legal in the US; FDA-Approved Clinical Research |
C | Observational studies |
| Addiction (opiods) | Noribogaine Not legal in the US |
B | Randomized Controlled Trials (1 or more) |
| Addiction (opiods) | Ibogaine Not legal in the US |
C | Observational studies |
Anxiety
Anxiety |
|||
| Substance | Evidence Level | Type of Evidence | |
|---|---|---|---|
| Ketamine Clinical Use Legal in the US |
B | Randomized Controlled Trials (1 or more) | |
Depression
Depression |
|||
| Substance | Evidence Level | Type of Evidence | |
|---|---|---|---|
| Ketamine Clinical Use Legal in the US |
B | Randomized Controlled Trials (1 or more) | |
| Psilocybin Not legal in the US; FDA-Approved Clinical Research |
B | Randomized Controlled Trials (1 or more) | |
End of Life Anxiety
End of Life Anxiety |
|||
| Substance | Evidence Level | Type of Evidence | |
|---|---|---|---|
| Psilocybin Not legal in the US; FDA-Approved Clinical Research |
B | Randomized Controlled Trials (1 or more) | |
Obsessive Compulsive Disorder
Obsessive Compulsive Disorder |
|||
| Substance | Evidence Level | Type of Evidence | |
|---|---|---|---|
| Psilocybin Not legal in the US; FDA-Approved Clinical Research |
C | Observational studies | |
PTSD
PTSD |
|||
| Condition | Substance | Evidence Level | Type of Evidence |
|---|---|---|---|
| PTSD | Ketamine Clinical Use Legal in the US |
B | Randomized Controlled Trials (1 or more) |
| PTSD | MDMA Not legal in the US; FDA-Approved Clinical Research |
B | Randomized Controlled Trials (1 or more) |
| PTSD with eating disorder | MDMA Not legal in the US; FDA-Approved Clinical Research |
B | Randomized Controlled Trials (1 or more) |
Suicidal Ideation
Suicidal Ideation |
|||
| Substance | Evidence Level | Type of Evidence | |
|---|---|---|---|
| Ketamine Clinical Use Legal in the US |
A | Systematic reviews and/or meta-analysis or society practice guidelines | |
Key: Levels of Evidence
| A | B | C | CR | E | T | X |
|---|---|---|---|---|---|---|
| Systematic reviews and/or meta-analysis or society practice guidelines | Randomized Controlled Trials (1 or more) | Observational studies | Case reports | Consensus or expert opinion, traditional use, not harmful | Theoretical use, not harmful | Evidence of harm, not recommended |
